解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Corticomotor evoked potentials have recently been used in experimental animals and patients as a measure of neurologic function after stroke. However, little is known about the fundamental electrophysiologic properties contributing to the formation of these potentials. To define some of these properties, corticomotor ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1141
更新日期:1987-11-01 00:00:00
abstract::A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase i...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1074
更新日期:1987-11-01 00:00:00
abstract::Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of strept...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1148
更新日期:1987-11-01 00:00:00
abstract::Results from 1,039 combined cervical and transcranial Doppler examinations are reported. Satisfactory transcranial signals were not found in 2.7% of the cases. Compared with angiography, the accuracy of transcranial criteria in assessing collateral flow over the circle of Willis was 94 and 88% for anterior and posteri...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1018
更新日期:1987-11-01 00:00:00
abstract::In children with Moyamoya disease, transient ischemic attacks often occur during hyperventilation, and the frequency of attacks usually decreases with advancing age. To elucidate the mechanism of the attacks, the regional cerebral blood flow was measured during rest and/or hyperventilation in children aged 3-16 with M...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.5.906
更新日期:1987-09-01 00:00:00
abstract::As part of a prospective study of mood disorders in stroke patients, interviews were obtained from 37 patients at 1 year and 48 patients at 2 years follow-up. In-hospital evaluations for these 65 follow-up patients found that 9 patients (14%) had symptom clusters of major depression, 12 patients (18%) had symptom clus...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.5.837
更新日期:1987-09-01 00:00:00
abstract::Using clinical presentation, angiography, computed tomography, and nuclear magnetic resonance imaging, 7 patients were identified who had strictly unilateral hemispheric infarction and unilateral cerebrovascular disease. In 6, cerebral blood flow measured by fluorine-18-fluoromethane inhalation and positron emission t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.5.882
更新日期:1987-09-01 00:00:00
abstract::We studied ultrastructurally cerebral perforating arteries in 60 stroke-prone spontaneously hypertensive rats (SHRSP), which were sequentially killed at 4-52 weeks of age before showing symptoms of stroke. Another 24 SHRSP were killed soon after they showed symptoms of cerebral infarction. The initial vascular lesions...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.733
更新日期:1987-07-01 00:00:00
abstract::As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.700
更新日期:1987-07-01 00:00:00
abstract::A 34-year-old, single Japanese woman with active Takayasu's disease presented with stenosed bilateral common carotid arteries, subtotal occlusion of the left subclavian artery, and complete occlusion of the ipsilateral proximal vertebral artery, as demonstrated by angiography. A right subclavian-left vertebral bypass ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.677
更新日期:1987-05-01 00:00:00
abstract::The authors report an autopsy case with repeated transient ischemic attacks and subsequent strokes demonstrating evidence of artery-to-artery embolism from thrombi generated in the stenotic middle cerebral artery to the distal cortical branches. This case substantiates the existence of intracranial artery-to-artery em...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.680
更新日期:1987-05-01 00:00:00
abstract::Fundus fluorescein angiography was performed in 10 cases of occlusive carotid artery disease at presentation and after surgery or medical treatment. An improvement in the microcirculation of the retina was observed in 4 cases after carotid endarterectomy and in 1 case after carotid endarterectomy and extracranial-intr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.585
更新日期:1987-05-01 00:00:00
abstract::A standardized neurologic assessment scoring instrument was developed and tested for use in a multicenter trial of hypervolemic hemodilution in acute hemispheric stroke. Components of the neurologic examination pertinent to hemispheric stroke syndromes were emphasized. The scale was evaluated using 16 acute stroke pat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.665
更新日期:1987-05-01 00:00:00
abstract::Functional assessment of animals following experimental cerebral ischemia is often difficult due to the passive nature of many neurologic exams. We attempted to increase the objectivity of motor function evaluation by adapting quantifiable behavioral tests and actively testing rats' motor capability following a cerebr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.2.503
更新日期:1987-03-01 00:00:00
abstract::Exposure of Mongolian gerbils to a 100% oxygen atmosphere after 15 minutes of global brain ischemia resulted in a marked increase in the production of pentane, an in vivo product of lipid peroxidation. Much less pentane production occurred in animals subjected to global brain ischemia then exposed to an air atmosphere...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.2.426
更新日期:1987-03-01 00:00:00
abstract::True, three-dimensional proton nuclear magnetic resonance imaging at 0.147 tesla was performed postmortem on 2 patients embodying various stroke syndromes, including chronic (4 and 15 years) infarction, subacute (within 1 week) bland infarction, acute (2 days) hemorrhagic infarction, and hematoma secondary to ruptured...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.2.342
更新日期:1987-03-01 00:00:00
abstract::Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in the birefringent amyloid deposits of the small arteries in the cerebrum, cerebellum, and leptomeninges of 10 Icelandic individuals with hereditary cerebral hemorrhage with amyloidosis....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.2.431
更新日期:1987-03-01 00:00:00
abstract::Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.46
更新日期:1987-01-01 00:00:00
abstract::The presence of hyperglycemia prior to stroke or cardiac arrest can increase neuronal damage caused by brain ischemia. Acute hyperglycemia shows this effect in animal models of stroke. However, chronic hyperglycemia and chronic hyperglycemia with additional acute elevation of blood glucose are more common premorbid st...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.52
更新日期:1987-01-01 00:00:00
abstract::Eighteen patients with recent ischemic stroke were compared with an equal number of matched controls. Standardized suspensions of red cells as well as of red and white cells were filtered in a new filtration apparatus capable of discriminating between cell deformability and filter occlusion. Results show that red cell...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.59
更新日期:1987-01-01 00:00:00
abstract::Spontaneous dissections of the extracranial internal carotid artery are diagnosed more frequently as their clinical and angiographic features are more widely recognized. Familial occurrence of spontaneous dissection of the internal carotid artery has not been previously reported. We describe the occurrence of this ent...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.246
更新日期:1987-01-01 00:00:00
abstract::Radiolabelled misonidazole, a radiosensitizing drug that binds to viable hypoxic tumor cells, may be useful in identifying hypoxic cells in cerebrovascular disease. Its potential was investigated in the gerbil stroke model. Biodistribution of [3H]misonidazole was measured in normal gerbils and animals that had been su...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.168
更新日期:1987-01-01 00:00:00
abstract::The postischemic production of PGE2, PGD2, 6-keto-PGF1 alpha, and TXB2 in brain tissue was studied in Mongolian gerbils using tissue extraction as well as a new ex vivo method. This new method permits the study of prostaglandin synthesis in slices from discrete areas of the brain (cortex, hippocampus, striatum, hypoth...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.111
更新日期:1987-01-01 00:00:00
abstract::As indicated by Barnett, Plum and Walton, a definitive clinical trial to resolve the issue of the effectiveness of carotid endarterectomy is clearly needed. A proposal to foster such a trial, through a moratorium on third-party reimbursement other than for randomized patients, has herein been presented. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.6.1335
更新日期:1986-11-01 00:00:00
abstract::To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the l...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.6.1254
更新日期:1986-11-01 00:00:00
abstract::In an attempt to determine the usefulness of evoked potentials as a measure of focal cerebral ischemia, we examined somatosensory evoked potentials (SEP's) and morphological neuronal changes in cats following unilateral middle cerebral artery (MCA) occlusion. Fifteen adult cats underwent transorbital occlusion of the ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.6.1193
更新日期:1986-11-01 00:00:00
abstract::In a case-control study of 73 cases of cerebral hematoma diagnosed by CT scan, significant risk factors were history of hypertension, chronic alcoholism, evidence of hepatic disease, EKG abnormalities and high hematocrit values. Initial blood pressure was significantly higher in cases, but blood pressure on the third ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.6.1126
更新日期:1986-11-01 00:00:00
abstract::The literature on carotid surgery for lesions appropriate to prior episodes of ischemia has been reviewed. Only one randomized study and six non-controlled reports give useful data (this despite more than thirty years of surgical activity in this field). When analyzed by the IMPS (intact months of patient survival) cr...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.17.6.1329
更新日期:1986-11-01 00:00:00
abstract::Cerebral venous blood gas tensions were correlated with elevated intracranial pressure in spontaneously breathing dogs lightly anesthetized with nitrous oxide/halothane. Intracranial pressure was elevated by infusion of artificial cerebrospinal fluid into a lateral ventricle. Respiration and blood pressure were monito...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.5.946
更新日期:1986-09-01 00:00:00
abstract::Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.5.976
更新日期:1986-09-01 00:00:00
abstract::Visually apparent EEG changes associated with clamping the internal carotid artery appeared in 55 of 176 consecutive patients (31%) undergoing carotid endarterectomy without shunt. Attenuation of higher frequency activity was the most common change. Changes were moderate in 33 patients (19%) and major in 22 (12.5%). M...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.5.891
更新日期:1986-09-01 00:00:00
abstract::The gerbil model was used to assess the therapeutic effects of the calcium antagonist nimodipine on cerebral ischemia. Transient cerebral ischemia was produced in each gerbil by bilateral common carotid occlusion of 10-, 15- or 20-min duration. Nimodipine (0.01 or 0.1 mg/kg) was administered intraperitoneally just bef...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.4.748
更新日期:1986-07-01 00:00:00
abstract::In the period 1977-1982, the Danish National Patient Register recorded 1000 cases of cerebral thromboembolic attacks among women 15-44 years of age, and 971 cases among men of the same age. Cerebral infarction accounted for 70% of cases and transient ischemic attacks (TIA) for the remaining 30%. By analysing this mate...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.4.670
更新日期:1986-07-01 00:00:00
abstract::The ejection fraction (EF) of the left ventricle was measured by radionuclide ventriculography in 64 patients during an acute cerebrovascular accident. Sixteen patients (12 with coronary artery disease) died within two weeks of the onset of symptoms and had only one EF measurement. In the remaining 48 patients, the EF...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.4.613
更新日期:1986-07-01 00:00:00
abstract::The influence of chronic arterial hypertension upon the permeability to albumin of the cerebral capillaries, i.e. the blood-brain barrier, was studied in normotensive Wistar and spontaneously hypertensive Wistar rats with experimental subarachnoid hemorrhage. The blood-brain barrier permeability to albumin was assesse...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.3.498
更新日期:1986-05-01 00:00:00
abstract::Of 171 patients evaluated prospectively and consecutively for cerebral ischemia, 26 (15%) developed symptoms while hospitalized. Cerebral ischemia complicated operative procedures in 12 patients, unsuccessful cardioversion in one and coronary angiography in another. Twelve patients had apparent cerebral embolism and 1...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.3.430
更新日期:1986-05-01 00:00:00
abstract::A multi-centered cooperative study is being undertaken to determine the role of carotid endarterectomy in the treatment of asymptomatic carotid stenosis. The primary objective is to compare the incidence of transient ischemic attacks, stroke, and death in previously asymptomatic patients with arteriographically confir...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.17.3.534
更新日期:1986-05-01 00:00:00
abstract::Various concentrations of acetylcholine (ACh) produced dose dependent relaxations of isolated, helical preparations of human cerebral arteries and these responses were blocked by atropine. The median effective concentration (EC50) of ACh was 6.1 +/- 0.2 X 10(-6)M. ACh produced dual responses in isolated dog cerebral a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.2.300
更新日期:1986-03-01 00:00:00
abstract::Experimental subarachnoid hemorrhage (SAH) was induced in baboons by repeated injections of autologous blood into cisterna chiasmatis and cisterna magna, a total of 14-33 ml being injected over 3-4 days. Cerebral blood flow (CBF; 133xenon clearance) and cerebral metabolic rate of oxygen (CMRO2) were measured before, a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.2.220
更新日期:1986-03-01 00:00:00
abstract::Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.2.207
更新日期:1986-03-01 00:00:00